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br Introduction Despite the widespread use of bone targeted
2019-05-18

Introduction Despite the widespread use of bone-targeted agents in the care of patients with bone metastases from prostate and breast cancer, questions regarding the optimal; choice of agent, dose, dosing frequency, and duration of therapy remain unanswered [1–6]. Our research group is interested
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Paying now rather than forever has never been
2019-05-18

Paying now rather than forever has never been as relevant as a global health solution to the HIV pandemic than in 2013. The relative success of the ongoing replenishment session for the Global Fund is a positive signal, although still insufficient considering the evidence-based targets that are set
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Lo que Jos Enrique Rod teoriz en Ariel Vasconcelos de
2019-05-17

Lo que José Enrique Rodó teorizó en Ariel, Vasconcelos, de niño en la escuela de Eagle Pass, pareció vivirlo en carne propia. En esta pelea “escuelera”, asociemos, ¿se asumía Vasconcelos betaxolol Supplier sí mismo como un Ariel, mientras a Jim, el gringo sanguíneo, lo consideraba como un Calibán?
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AM251 br La historia de los animales en
2019-05-17

La historia de los animales en el Nuevo Mundo La descripción de la AM251 americana fue una tarea que realizaron algunos exploradores, soldados, funcionarios y religiosos como respuesta a la petición de información de las autoridades, deseosas de conocer la fauna y descubrir las propiedades de la
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The study by Mijiti and colleagues also
2019-05-17

The study by Mijiti and colleagues also illustrates that, besides medical factors, social determinants of health—poverty, education, geography, customs, etc—also play an important role in tuberculosis control. Owing to the low socioeconomic status and poor social health environment, tuberculosis mai
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Even with the limitations in the available data on
2019-05-17

Even with the limitations in the available data on DALYs, the funding gap is huge. The Research Investments in Global Health study analysed public and philanthropic infectious disease research awards to UK institutions (1997–2013), and compared them to the burden in DALYs, describing a new metric of
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En definitiva se trataba de buscar un origen de
2019-05-17

En definitiva, se trataba de buscar un “origen” de la literatura y cultura latinoamericana, no afincado en las textualidades del siglo xix o en un momento tar-docolonial, sino en aquellos textos “fundantes” en los que todo parecía posible: las crónicas de conquistadores y soldados, los conmovedores
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br Conflict of interest br Introduction Landiolol is an
2019-05-16

Conflict of interest Introduction Landiolol is an intravenous short-acting beta-adrenoreceptor blocker, and its wide use is exhibited by rapid wash out and a less-sustained effect on cardiac function after decreasing the dose or stopping its administration [1]. We present a patient with drug-r
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It is good to see any cluster randomised community
2019-05-16

It is good to see any cluster-randomised s ibuprofen trial of a handwashing intervention, much more a successful one. Globally there is considerable funding invested in handwashing promotion, yet the kind of rigorous study published in this month\'s issue of by Adam Biran and colleagues is rare in
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br Tuberculosis remains a global emergency and continues
2019-05-16

Tuberculosis remains a global emergency and continues to present major public health challenges worldwide. The actual global burden of tuberculosis can only be estimated because no accurate data are available from national country programmes from of high tuberculosis endemic countries. The WHO 201
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Permanent pacemaker implantation with trans IVC
2019-05-16

Permanent pacemaker implantation with trans-IVC access was first reported in 23 cases by Ellestad et al., in 1980 [2]; it was then reported in 95 cases, of which the early cases were published in 1989 by the same author as the largest series reported thus far [5]. Mathur et al. also reported 27 case
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Current ASCO recommendations suggest initiating bisphosphona
2019-05-16

Current ASCO recommendations suggest initiating bisphosphonate therapy in myeloma when there is evidence of bone involvement [124]. The optimal duration and frequency of bisphosphonate therapy for myeloma are not well understood and are currently being studied. All randomized, placebo-controlled tri
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ep4 receptor Several anti platelet therapies have been evalu
2019-05-16

Several anti-platelet therapies have been evaluated in the context of bone metastasis. In vitro, a dual anti-platelet treatment using the soluble ADPase APT102 and an inhibitor of TxA2 synthesis (Aspirin) markedly affected tumor cell-induced platelet aggregation without altering tumor cell viability
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br Discussion CRT has become
2019-05-16

Discussion CRT has become an established adjunctive treatment to optimal pharmacological therapy in patients with advanced CHF, diminished LV function, and intra-ventricular conduction delay [8]. Despite the benefits of CRT including improvements in exercise capacity, functional class, and ventri
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Houve uma tentativa por aglutinar as fra
2019-05-15

Houve uma tentativa por aglutinar as frações mais radicais da esquerda em torno da Alianza Revolucionaria de Izquierda (ari), tendo em vista as eleições presidenciais de 1980. No entanto, esta aliança só durou três meses e foi rompida por diferenças mesquinhas entre as dirigências políticas, o que g
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